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How to Rationally Approach Supplementation for Sleep, Hormone Support, and Cognitive Enhancement Sleep Huberman suggests that if youre thinking about supplementation for sleep, you first need to optimize your behavioral and nutritional protocols, such as avoiding caffeine after 2 pm and avoiding food two hours before bed, as these can disrupt the architecture of sleep. Once these protocols are met, Huberman says you need to ask yourself a few questions

Maintaining balanced IGF-1 + IGFBP-3 levels supports healthy tissue repair without tipping into excessive growth

Therapeutic use of the ketogenic diet in refractory epilepsy: what we know and what still needs to be learned

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