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Should ketamine be reserved for the most refractory headache disorders or introduced earlier in the treatment algorithm with more liberal use

Common Adverse Reactions ( 2%): vaginitis (13.8%), headache (including migraine) (11.2%), mood changes (e.g., depression, mood swings, mood altered, depressed mood, affect lability) (6.4%), device-related events (e.g., expulsion/discomfort/foreign body sensation) (6.3%), nausea/vomiting (5.9%), vaginal discharge (5.7%), increased weight (4.9%), vaginal discomfort (4.0%), breast pain/discomfort/tenderness (3.8%), dysmenorrhea (3.5%), abdominal pain (3.2%), acne (2.4%), and decreased libido (2.0%)

Drink fluids on a schedule (4-6 ounces per hour while awake) rather than waiting for thirst, and choose electrolyte-containing fluids when sick