Pancreas GLP-1 and GIP stimulate insulin secretion GLP-1 suppresses glucagon secretion during hyperglycemia GIP suppresses glucagon secretion during hyperglycemia and stimulates secretion during euglycemia and hypoglycemia Brain GLP-1 and GIP suppress hunger Stomach GLP-1 slows gastric emptying Fat tissue GIP increases fatty acid and glucose uptake by fat tissue [1,2,3] Tirzepatide Tirzepatide is a dual GLP-1 / GIP receptor agonist that mimics the actions of GLP-1 and GIP
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Eapen, MD, says, Many patients take medication for at least 6-12 months, but some may need longer-term management
[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Moulton C.D., Rokakis A.S., Pickup J.C., Young A.H., Stahl D., Ismail K