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The mechanism operates through multiple pathways simultaneously

Laboratory markers include suppressed free T3 with normal TSH (euthyroid sick syndrome), elevated cortisol, and in severe cases, low LH and FSH indicating hypothalamic suppression

10.1038/s41423-020-0488-6 Summary Keywords prostate cancer, peptide, immunotherapy, tumor microenvironment, immunogenic cell death Citation Li X, Yang F, Wang M, Huang X, Zeng X, Zhou L, Peng S and Zhang J (2025) Unleashing the power of peptides in prostate cancer immunotherapy: mechanism, facts and perspectives

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