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High levels of oxidative stress may contribute to ALS onset, increasing motoneurons death, and heavy metals may be a cause for the increase of ROS

For evidence of impact on patient outcomes, we agree with commenters that it is critical to ensure that quality measures are supported by sufficient evidence

Diagnostic features: Multi-loculated cyst(s) lined by fine septa containing fine flocculent eosinophilic material (PAS-positive)

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