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Some studies have found a large number of circadian rhythmically expressed genes in the liver, which are involved in maintaining the metabolic balance of the body

Effect of long-acting liraglutide QD on HR A 24-h time-averaged increase in mean placebo- and baseline-adjusted HR of 78 bpm was reported following liraglutide 1.2 and 1.8 mg QD (titrated in 0.6-mg weekly steps) using serial ECG monitoring at the end of the second and third weeks (after the seventh and final dose) of liraglutide (N = 51)

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Of course, since the goals may be different for each type of patient, theres a chance that many dietitians will end up with one group or the other by default