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The NADP binding site is located near a fan of -sheet structures, with a critical G-X-X-G-X-X peptide motif corresponding to amino acids 38 to 43 encoded in exon 3

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Access this article Similar content being viewed by others Data Availability The data that support the findings of this study are available on request from the corresponding author, Paccou J

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It aids in the metabolism of fats, helps reduce blood cholesterol, and participates in the action of serotonin

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Therefore, GPX4 activation could be used as a new anti-inflammatory or cytoprotective therapy (Fig

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