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For example, a patient may notice that weight gain began after menopause, sleep disruption, an injury, a medication change, a stressful period, or a change in activity level

American Journal of Clinical Nutrition, 90 (5), 12361243

It is currently advancing through Phase 3 clinical trials for obesity treatment

The same starting dose applies postpartum, but the duration at each level typically extends: Weeks 1 through 8: 2.5 mg weekly Weeks 9 through 16: 5 mg weekly Weeks 17 through 24: 7.5 mg weekly Weeks 25 and beyond: 10 mg weekly (if needed) Maximum dose: 15 mg weekly Many postpartum women find that 5 mg or 7.5 mg is their effective maintenance dose and do not need to escalate to 10 or 15 mg