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10.3390/gastroent12010006 126 TrebickaJ.MacnaughtanJ.SchnablB.ShawcrossD

Brown, A review of dietary (Phyto)nutrients for glutathione support, Nutrients , vol

The phase 3 TRIUMPH-4 data showed these rates at 9 mg and 12 mg doses respectively: Nausea: 38.1% and 43.2% (vs 10.7% placebo) Diarrhea: 34.7% and 33.1% (vs 13.4% placebo) Constipation: 21.8% and 25.0% (vs 8.7% placebo) Vomiting: 20.4% and 20.9% (vs placebo) These numbers are higher than cagrilintide monotherapy across the board

In fact, studies in young animals and infants have shown that approximately half of the dietary glutamate and glutamine is oxidized by intestinal and immune cells, ultimately leading to the generation of energy for the cells to adequately function and grow (87)