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Fahed DC, Ghazi NG, Jabbour NM, Fahed CD, Fahed JC, Salti HI

Deregulated activation of c-Met contributes to a few aspects of tumor progression, such as inducing neoplastic cells to disaggregate from the tumor mass, eroding basement membranes, infiltrating stromal matrices, and finally colonizing new tissues to form metastases ( Onset Chronic liver diseases such as cirrhosis and hepatitis B or C are triggers of HCC ( N -nitrosodiethylamine-induced HCC (Takami et al., 2007)

After sonicating (1400 rpm, 20 C, 5 min), the extracts were cleared by centrifugation (17,000 g , 20 C, 10 min), and the lipids in the supernatant were analyzed by LC-MS