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Pavicic and colleagues compared topical hyaluronic acid formulations across five molecular weights (50, 130, 300, 800, and 2000 kDa) in 76 women aged 30 to 60 over 60 days
PubMed Central, doi:10.1016/bs.apcsb.2019.01.001
A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]
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