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To confirm the prediction accuracy of the established model, we applied the model to an independent validation cohort comprising 50 patients with CVD who had received OCCT by using urine samples (Figure S8)

However, some research indicates that although BBR has certain effects on the microstructure and bone formation markers of the tibial diaphysis in diabetic rats, it did not improve bone mineralization and biomechanical properties (Londzin et al., 2022)

This methodology is based on anthropomorphic assumptions that animals require a period of resting time to feel happy and respond to chemical cues after handling stress such as the placement into the behavioral arena (Wilson et al., 2021)

2000 Svensson J et al