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The difference is just the count: tirzepatide hits two, retatrutide hits three
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Effect of oral semaglutide compared with placebo and subcutaneous semaglutide on glycemic control in patients with type 2 diabetes: a Randomized Clinical Trial
One sublingual-specific consideration: niacinamide can cause flushing (warmth and redness in the face and upper body) in some people, and sublingual absorption may increase the likelihood of flushing compared to injectable because the niacinamide enters the bloodstream more rapidly
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