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ORiordan W, McManus A, Teras J, Poromanski I, Cruz-Saldariagga M, Quintas M, Lawrence L, Liang S, Cammarata S, PROCEED Study Group

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As a long-term consequence of ligature-induced periodontitis, not only tissue gingival inflammation measured by extravasation increased but there was also a considerable bone loss in the periodontium

Chronic inflammation is the underlying cause of many health issues, including autoimmune disorders and metabolic disorders