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It has demonstrated efficacy in various malignancies, including non-small cell lung cancer, small cell lung cancer, soft tissue sarcoma, and medullary thyroid carcinoma (1318)

The limited absorption of the nasal cavity restricts the amount of drug being effectively absorbed, making class I drugs (high permeability, high solubility), according to the Biopharmaceutics Drug Disposition Classification System (BDDCS), particularly suitable for nasal delivery (Ugwoke et al., 2001)

Moreover, it is known that the meniscus anatomy is divided into three zones which have different degrees of vascularization (red-red vascularized zone vs

An efficient brain requires a stable energy flow