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GLP-1RAs are known to delay gastric emptying a condition in which the stomach empties slower than normal potentially leading to the presence of residual gastric content (RGC) in appropriately fasted patients

Nauck MA, Heimesaat MM, Behle K, Holst JJ, Nauck MS, Ritzel R, Hfner M, Schmiegel WH: Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers

Effect Patients on Zepbound (tirzepatide) 5mg weekly lost 16.1 kg (35.5 lb) on average after 72 weeks

An attractive feature of colchicine is how specific it is