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While synthetic antioxidants play a pivotal role in food preservation and industrial application, their medical use remains restricted due to potential health concerns, necessitating further research into safer and more effective formulations

Although diosgenin is the nonpolar steroidal compound, it takes 1 h to reach the T max due to higher number of OH groups in compound making it more polar as compared to the charantin

Recent advances in redox proteomics have identified novel biomarkers like peroxiredoxin-3 oxidation that predict neuropathy progression 5 years before clinical onset ( 7 Clinical trial protocol design for antioxidant therapy in hypertension and diabetes The selection of appropriate OS biomarkers is critical for assessing the efficacy of antioxidant therapies employed in the treatment of HTN and DM from the results of clinical trials

Dietary Changes: Make necessary changes to your diet by including B12-rich foods like meat, eggs, dairy products and other sources of B12