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However, the green areas located outside the built structures are often incorrectly delineated due to their nature and labelled as water areas, so that the pre-trained model achieves an overall accuracy of 46%

10.1016/j.freeradbiomed.2014.11.019 [DOI] [PubMed] [Google Scholar] Statista

This is not a strict requirement, but rather an observed pattern that helps reduce nausea

The Need for New Formulations Because of these quite dramatic and potentially efficacious effects, and the urgency of the COVID19 pandemic, in addition to simply repurposing the original oral tablets, there have been efforts to develop new formulations and routes of administration for niclosamide, to validate them in preclinical studies, and clinically test niclosamide for COVID-19 (see this reference to clincaltrials.gov (35))