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IM provides faster systemic peaks when timing matters more than duration but comes with significantly higher injection site pain that affects adherence

On the contrary, miR-138 (192), miR-142-3p (198), miR-98 (201), miR-26a-5p (203), miR-191 (205), miR-15 (222), and miR-483-3p (282) enhance the inflammatory milieu and subsequently tissues could be damaged