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Key Takeaways Oral semaglutide is a promising new weight loss medication, expected to be the first oral GLP-1 treatment for obesity, demonstrating significant efficacy in clinical trials with a potential weight loss of up to 15%

No cloudiness indicates peptide aggregation, copper salt precipitation, or microbial contamination, all of which mean the peptide-copper complex is no longer intact and soluble

The injection site should always be cleaned with an alcohol swab and allowed to dry before injecting

3 * Based on the efficacy estimand: estimated efficacy in an idealized scenario in which all patients stayed on treatment and without initiation of additional glucose-lowering medication