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[1] [2] Semaglutide has an additional warning regarding worsening of diabetic retinopathy complications, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose

Patients with significant gastroparesis, a condition involving delayed gastric emptying, may find that GLP-1 medications significantly worsen their symptoms given the medication's mechanism of action

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The degree of weight loss was independently associated with statistically significant improvements in all NASH-related histologic parameters and provides strong evidence that weight loss is an effective treatment for NAFLD