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Aug 7 2025;393(6):533-543

Currently, there are no effective treatments for SIM, with a focus on prevention, commonly involving blood glucose control, early anti-inflammation treatment, early enteral nutrition, and early exercise and rehabilitation (13)

Related research context BPC-157 is part of the peptide-based healing and tissue repair research class, commonly studied in models involving angiogenesis, extracellular matrix remodeling, and soft-tissue recovery

This is corroborated by setmelanotides clinical trials, where participants with monogenic obesity or HO respond more strongly to treatment than general obese participants (NCT02041195, NCT01749137) (87, 9094)