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From its potential benefits for immune function, detoxification, anti-aging, athletic performance, chronic illnesses, and cancer, its no wonder why more and more individuals are considering this therapy

10.1038/ng0595-111

However, only 22% of the variation in MMA levels was explained by vitamin B12, estimated glomerular filtration rate, age, sex, and socioeconomic status, suggesting that other underlying disease was likely the reason for elevated MMA levels

This suggests that tesofensine may have two components: one anorexigenic and a second that stimulates energy expenditure, the latter perhaps mediated by its NE component [2, 61]