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In both of these studies, CagriSema was well-tolerated with an acceptable safety profile, with similar results reported in a phase 1b study in participants with overweight or obesity [7] and a phase 2 study in participants with type 2 diabetes [4]

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Tirzepatide distinguishes itself by acting as a dual agonist, engaging both GLP-1 and GIP receptors

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fat oxidation) during high-intensity exercise

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These included both mitochondrial and peroxisomal fatty acid oxidation genes (Figure 3C)

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