The reasons are multifactorial: chronic inflammation damages blood vessel walls, corticosteroid use raises cholesterol and blood pressure, lupus-specific antibodies (particularly antiphospholipid antibodies) increase clotting risk, and the metabolic disruption caused by both the disease and its treatments creates a perfect storm for atherosclerosis
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Insert the needle, draw your dose, then withdraw the needle without injecting air back into the vial to equalize pressure
Exendin-4 Ex-4 has been shown to enhance pancreatic beta-cell marker expression (pancreatic and duodenal homeobox 1 ( PDX-1 ), NK2 homeobox 2 ( NKX2.2) , ISL LIM homeobox 1 (I SL-1 ) and v-Maf musculoaponeurotic fibrosarcoma oncogene homolog A ( MAFA)) [35,36,37]