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46,47 However, long-term use has been reported to alter bone metabolism and increase fracture risk 48 and increase mortality in patients with heart failure due to its fluid retention effects

Dosage and Duration of Use: Someone on a higher maintenance dose who has been on the medication for a year will have a more established steady-state concentration than someone who only took a low starting dose for a few weeks

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Ipamorelin is a selective growth hormone secretagogue a peptide that stimulates your pituitary gland to release stored growth hormone in a controlled, pulsatile fashion