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A meta-analysis which included eight trials with a total of 60,080 patients found that GLP-1 agonists reduced major adverse cardiovascular events, all-cause mortality and hospital admissions for heart failure in treated patients with type 2 diabetes, regardless of structural homology 20

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In May 2022, tirzepatide (marketed as Mounjaro) received FDA approval for improving blood sugar control in adults with type 2 diabetes, in combination with diet and exercise

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