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Subsequent studies have focused on KPV's effects in gut inflammation models, where it reduced mucosal inflammation markers without causing immunosuppression

doi: 10.4049/jimmunol.178.12.7649

13 Studies investigating the status of claudins and other TJ-associated proteins in human biopsy specimen from chronic inflammatory conditions (Inflammatory Bowel Disease (IBD)) 14 have demonstrated differential changes in their total cellular content and/or distribution (see Table 1)

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