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Moreover, the floral extract and the polyphenol fraction exhibit significant anti-inflammatory properties as they suppressed cytokine release (IL-6, TNF-, IL-8) from HCE-T and human acute monocytic leukemia cell lines (THP-1) and the activity of NF-B and calcium influx in THP-1 and Jurkat cells were diminished

However, this combination requires careful consideration of individual patient factors and potential overlapping effects

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93 Consistent with these data, JNK inhibitors were shown to prevent nitrotyrosine staining and effectively protect against APAP-induced liver injury