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2 Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia 3 Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia 4 ShemyakinOvchinnikov Institute of Bioorganic Chemistry, 117997 Moscow, Russia 5 Institute of Functional Genomics, Lomonosov Moscow State University, 119991 Moscow, Russia * To whom correspondence should be addressed

Inhibiting NNMT with 5-amino-1MQ reverses this: NAD+ levels rise, mitochondrial respiration increases, and white adipose tissue (fat storage) shifts toward thermogenesis

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Fibroids are found in 20% of women of reproductive age but are more common in African-American women (50%-80%)