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Keywords: aspirin, cancer therapy, signaling pathways, nanotechnology, targeted drug delivery Introduction Aspirin (acetylsalicylic acid, C 9 H 8 O 4 ) 1 is one of the most widely used medications worldwide, known for its analgesic, 2 anti-inflammatory, 3 and antipyretic effects

154 Aspirin has also been shown to modulate the miR-98/WNT1 axis, suppressing the target gene WNT1 and inhibiting lung cancer cell viability and colony formation, providing a novel mechanistic explanation for its antineoplastic effects