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DGEA, engineered to express a heptaglutamate domain, was found to accumulate within bone tissue following intravenous injection [168], suggesting that such an approach could be used for drug to bone delivery

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In the brain, similar to other tissues, LCFA transport across membranes requires various proteins, such as fatty acid transport protein (FATP), fatty acid translocase (FAT)/CD36, plasma membrane-bound fatty acid binding protein (FABPpm), and cytosolic fatty acid-binding protein (FABPc) (123)

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