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As individual peptide chains unfold, hydrophobic residues that were buried in the core become exposed to the aqueous environment

The primary outcome measure was overall response rate according to Response Evaluation Criteria In Solid Tumors (RECIST, version 1.1) criteria as assessed by blinded independent central review.[1][Level of evidence B3] The overall response rate was 26% (95% confidence interval [CI], -14 to 13