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Therefore, we investigated DNA damage in the Achilles tendon by immunostaining for H2AX, a sensitive marker of DNA damage

Mechanism: Enlarges hair follicles (reverses miniaturization) Stimulates follicular cell proliferation Increases angiogenesis around follicles Acts as powerful antioxidant Reduces inflammation Inhibits 5-alpha-reductase (the enzyme that converts testosterone to DHT) Studies show GHK-Cu can increase follicle size by up to 30% and significantly increase the percentage of follicles in anagen phase

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However, 15% to 20% of ER+ tumors are intrinsically resistant to endocrine treatment while 30% to 40% of ER+ tumors develop endocrine resistance to this class of drugs throughout treatment [9, 10]