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Data obtained from several trials and meta-analysis studies on beta-carotene and vitamin E (ATBC trial) indicate that while vitamin E is not effective in cancer prevention, beta-carotene may even increase the incidence of lung cancer among smokers (see also above)

They illustrated that 100 mg/d riboflavin supplementation during 3 months had a similar effect to propranolol intervention, and also riboflavin supplementation would be a safe intervention for migraine prevention (35)

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