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Individual factors significantly influence how fluoxetine affects your weight, including: Your baseline weight and metabolic rate The severity of depression, anxiety, or eating disorder symptoms Dietary habits and physical activity levels Genetic factors affecting drug metabolism Concurrent medications It is important to note that weight changes associated with fluoxetine are generally modest compared to some other antidepressants

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Losing weight through a structured medical weight loss program can improve or even reverse conditions like type 2 diabetes, high blood pressure, and elevated cholesterol

Diabetes reduces the numbers of spermatogenic cells, Sertoli cells, and Leydig cells, further diminishing sperm motility and serum testosterone levels [39, 40]