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DOI: 10.1038/nrn2038 54
This review article aims at discussing the potential of therapeutic GLP-1 receptor agonists in alleviating depressive symptoms in the context of modern theories surrounding the pathogenesis of this disease and explores their influence on cognitive processes, neurotransmission, modulation of neuroinflammatory processes, effects on HPA axis activity, brain energy balance, and the functioning of the gut-brain axis
The peptide remains localized in the epidermis and upper dermis for 4896 hours, binding to dermal collagen and elastin to create a tissue reservoir
The mechanism by which oral glutathione reaches skin tissue to modulate pigmentation and oxidative stress [72] has been presented and reviewed elsewhere [65, 73]
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