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337 Concurrently, age-related decreases in PINK1/Parkin-mediated mitophagy promote oxidative stress and mitochondrial dysfunction, which can trigger synovial inflammation and reduce the osteoclast activity critical for healthy bone remodeling, thereby contributing to joint damage and motor impairment

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2 Scientific studies have shown connections between the use of GLP-1 drugs and an increased risk of gastrointestinal issues, 3 including gastroparesis

Doctors increasingly see obesity as a chronic condition that needs sustained treatment