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It is not currently approved for type 2 diabetes in the US, though Lilly has stated its intention to file for that indication during 2026

In GD, the major autoantigen (thyroid-stimulating hormone (TSH)-antibody) is to the receptor for the TSH, which causes overproduction of thyroid hormones, resulting in symptoms such as irritability, rapid heartbeat, weight loss, poor tolerance of heat and bulging eyes (Graves orbitopathy) ( Reference Effraimidis and Wiersinga 4 , Reference Marcocci, Kahaly and Krassas 7 , Reference Brent 8 )

doi: 10.1152/ajpendo.00499.2003 151 UrvaSCoskunTLoghinCCuiXBeebeEO'FarrellLet al

FGF21 regulates sweet and alcohol preference