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It finds the problem

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Even among those who are prescribed treatment, only about half take the medication beyond one year

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Controlled uncoupling with modified dinitrophenol analogs (e.g., DNP-Mito) reduced mtROS by 65% while maintaining ATP synthesis in hypertensive rat models ( Experimental gene therapies delivering antioxidant enzyme genes (e.g., CAT, SOD, GPx) via viral vectors or nanoparticle carriers have shown promise in animal models by bolstering intrinsic defenses (Padmanaban et al., 2023)

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