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Consequently, antioxidant enzymes and non-enzymes, including glutathione peroxidase (GPX) and mitochondrial enzymes, are depleted, while mitochondrial damage in liver tissues and serum levels of intracellular liver enzymes increase such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT)

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Increased Energy Expenditure : Amphetamines can raise basal metabolic rate by 10-15% through thermogenic effects