These all have side effects, but the biggest challenge with them is that they are daily oral medications, which can be forgotten, missed, or hard to adhere to
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These include: Ergotamine or ergot derivatives like dihydroergotamine (Migranal, Ergomar) Other triptans such as sumatriptan (Imitrex), rizatriptan (Maxalt), zolmitriptan, naratriptan, frovatriptan, or almotriptan within 24 hours Strong CYP3A4 inhibitors such as ketoconazole (Sporanox), itraconazole, clarithromycin, ritonavir, nelfinavir (Viracept), and nefazodone These drug interactions can increase eletriptan levels in the body and raise the risk of serious side effects, including coronary artery vasospasm and arrhythmias
It is worth noting that HA exhibits favorable lubricating properties, particularly when cross-linked, as it forms a liquid matrix on the ocular surface