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Methods We searched for peer-reviewed, scientific papers, reports, and reviews using combinations of key terms such as child undernutrition, severe acute malnutrition (SAM), kwashiorkor, wasting, marasmus, pediatric obesity, endocrine alterations, immune dysfunction, epigenetics, DNA methylation, histone modifications, inflammation, and gut microbiome or microflora, metabolic outcomes, transgenerational effects and therapeutic approaches

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Laboratory research has examined Alzheimers-related pathways, but clinical prevention has not been demonstrated