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How autophagy controls the intestinal epithelial barrier

10.1089/ars.2016.6866 82 YuF.YuC.LiF.ZuoY.WangY.YaoL.et al (2021)

Tirzepatide activates both GLP-1 and GIP receptors, potentially triggering stronger appetite suppression than semaglutide alone, especially if your genetic profile favors GIP-pathway sensitivity

Although high microbial diversity is usually associated with better health outcomes, it also possibly causes destructive effects, such as increased protein breakdown and decreased polyphenol conversion, mucus secretion, and epithelial turnover [40]