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These conditions digestive conditions, such as Crohns disease and ulcerative colitis autoimmune conditions, such as celiac disease and type 1 diabetes genetic conditions, such as inherited intrinsic factor deficiency and inherited transcobalamin deficiency chronic pancreatic disease pernicious anemia vitiligo Other factors that may lead to a vitamin B12 deficiency can include drinking excessive amounts of alcohol or using certain drugs, such as some heartburn medicines and metformin

Bone turnover markers: Osteocalcin (bone formation), CTX (bone resorption)

Ultimately, understanding your body and working with a trusted provider is the best path forward

Mechanisms Evidence shows MOTS-c: (Lee et al., 2015