On the regulatory side, the European Food Safety Authority (EFSA) has authorised a claim that glucomannan contributes to weight loss in the context of an energy-restricted diet at 3 g per day taken in three 1 g doses with water, subject to a mandatory choking warning for anyone with swallowing difficulty or inadequate fluid intake, and an authorised oat beta-glucan claim for maintenance of normal blood cholesterol at 3 g per day [6]
It works as a very selective GLP-1 receptor agonist and is very similar to human GLP-1 (94% similarity)
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(PubMed) Polymeropoulos E, Bagos P, Papadimitriou M, Rizos I, Patsouris E, Tauoumpoulis I