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These studies not only indicate a role for the gut microbiota in impacting gutbrain neuronal signaling, but also suggest that differential gut microbiomes could have varying effects

Subsequently, caspase-1 is activated, which in turn cleaves Gasdermin D (GSDMD), leading to cell membrane perforation and release of interleukin-18 (IL-18) and IL-1, ultimately resulting in cell swelling and pyroptosis (Liu et al., 2024)