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But over time, such deficiency may cause anemia, nerve damage, and even problems with memory and reasoning

However, due to their higher incidence of side effects , TCAs are not first-line treatments for depression and are generally reserved for cases where newer antidepressants (e.g

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Recent advances in high-throughput sequencing and metabolomics have elucidated mechanisms linking gut microbiota and associated metabolites to kidney and brain health, revealing the role of microbial diversity and metabolite profiles in disease outcomes