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In addition, if lycopene and alpha-tocopherol have similar antioxidant functions (fat-soluble antioxidants), lycopenes potential antioxidant action is redundant to alpha-tocopherols antioxidant function and thus, also less likely to be a meaningful antioxidant

Particularly for heart failure, several clinical trials and meta-analyses have already confirmed that SGLT2is reduce HHF by approximately 30% in both HFrEF and HFpEF, with or without diabetes [46]

Ann Rheum Dis (2010) 69(11):20136

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