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Notably, there was a significant decrease (7.5%) in AA in striatal tissues but a significant increase (18%) in SNcVTA tissues in mutants compared with controls (Fig

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Results: The models explain why women of childbearing age have higher glutathione than men, and that this is caused by the balance of activation of glutamyl cysteine synthetase (GCL) and glutathione peroxidase (GPX) by estradiol

If the reaction is considered in isolation, a negative relationship between the GSH:GSSG ratio and DHAR activity would be predicted, because the enzyme consumes GSH and produces GSSG